吳冠賢 Kuan-Hsien Wu

Kuan-Hsien Wu is a Ph.D. student in the Department of Biomedical Engineering at National Taiwan University and a research assistant in the Orthopaedic Engineering and Movement Intelligence Laboratory. He received his B.S. degree from National Cheng Kung University and his M.S. degree from NTU before continuing into the doctoral program. He also collaborates clinically as a research assistant at Shin Kong Wu Ho-Su Memorial Hospital.

His research focuses on integrating biomechanics, dynamic fluoroscopic imaging, and statistical shape modeling to investigate in vivo joint mechanics with high spatial accuracy. He develops imaging and computational methods for quantifying knee and ankle joint behavior, including 3D–2D registration, articular contact analysis, ligament length assessment, and personalized bone–cartilage morphology reconstruction. His work contributes to the advancement of imaging-based motion analysis pipelines and calibration systems for lower-limb joint biomechanics.

Kuan-Hsien has published in journals such as Medicine & Science in Sports & Exercise, Frontiers in Bioengineering and Biotechnology, and Scientific Reports, and has presented his work at major international biomechanics and sports medicine conferences. He has also contributed to multiple national research projects spanning robot-assisted arthroplasty, cruciate ligament biomechanics, and ankle implant development. He is a co-inventor of the Taiwanese patent “Measurement System and Method for Personalized Bone and Articular Cartilage Morphology.”

[1] TW Lu, KH Wu, MY Kuo, JD Li, HY Lu, HC Hsu. Biomechanical Interactions Between Bones, Patellar  Tendon, and Cartilage Surfaces at the Knee During Cycling as Revealed by Three-Dimensional  Fluoroscopic Imaging.  Med Sci Sports Exerc. 2025  

[2] PA Lee, TM Wang, YT Chen, KH Wu, TM Wang, HC Liu, TW Lu. Mid-vastus total knee arthroplasty  for medial osteoarthritis recovers gait balance control better than lateral parapatellar approach three  months post-surgery. Frontiers in Bioengineering and Biotechnology, 2023, 11: 1133992.  

[3] PA Lee, KH Wu, HY Lu, KW Su, TM Wang, HC Liu, TW Lu. Compromised balance control in older  people with bilateral medial knee osteoarthritis during level walking. Scientific reports, 2021, 11.1:  3742.  

[1] KH Wu, MY Kuo, JD Li, HY Lu, HC Hsu, TW Lu. Kinematic Interactions Between Bones, Patellar Tendon,  and Cartilage Surfaces During Cycling by Three-Dimensional Fluoroscopic Imaging. 2024, The American  College of Sports Medicine Annual Meeting, Boston, United States  

[2] KH Wu, HY Lu, MY Kuo, CC Lin, HC Hsu, TW Lu. Development of a Statistical Shape Model of the  Knee for Predicting Bone/Cartilage Morphology and Articular Contact Trajectories During Activities.  2023, 29th International Society of Biomechanics, Fukuoka, Japan  

[3] KH Wu, TW Lu. Changes in ACL and PCL Length During Different Cycling Seat Height and Resistance.  2022, 9th World Congress of Biomechanics, Taipei, Taiwan  

[4] SH Lee, HY Lu, YH Chen, KH Wu, TW Lu. Biomechanical Analysis of Osteoarthritic Knees after Mobile  Bearing Unicompartmental Knee Arthroplasty during Activities Using 3D Fluoroscopy. 2022, 9th World  Congress of Biomechanics, Taipei, Taiwan  

[5] HC Hsu, HY Lu, CC Lin, MY Kuo, MT Huang, KH Wu, PL Weng, TL Chang, HM Tseng, TW Lu. Three Dimensional Reconstruction of Personalized Knee Surface Model Using Biplane Fluoroscopy and  Statistical Shape Modeling: Applications to Older Healthy Adults and Those with Uni-Compartmental  Arthroplasty. 2022, 9th World Congress of Biomechanics, Taipei, Taiwan  

[6] KH Wu, HY Lu, MY Kuo, HC Hsu, TW Lu. Reconstruction of the Ligament Attachment of the Knee by  Using Statistical Shape Model. 2022 Taiwanese Society of Biomechanics Annual Conference, Kaohsiung,  Taiwan  

[7] HY Lu, MY Kuo, KH Wu, MT Huang, HC Hsu, TW Lu. Comparisons of Rigid Body Kinematics Between  Robot-Assisted Uni-Compartmental Knee Arthroplasty and Total Knee Replacement During Sit-To-Stand  Using Biplane Fluoroscopy. 2022 Taiwanese Society of Biomechanics Annual Conference, Kaohsiung,  Taiwan  

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